The following reagents are available for research purpose from the investigators of the NIAMS-sponsored Consortium for Translational Research in Marfan Syndrome. - Fibrillin-1 mutant mouse line mgR is available from the Jackson Laboratories, and fibrillin-1 mutant mouse line mg is available by making request to Francesco Ramirez. (ramirefr@umdnj.edu)
- Monoclonal antibodies for human fibrillin-1 (mAB26) and for fibrillin-1 in a variety of species (mAb69) are available from Chemicon. Additional monoclonal antibodies or polyclonal antisera are available on a limited basis, or for extensive studies, on a collaborative basis, by making request to Lynn Sakai. (LYS@shcc.org)
- TGF-ß reporter cell line, and monoclonal antibodies for human TGF-ß1 LAP are available by making request to Dan Rifkin. (rifkid01@med.nyu.edu)
- Fibrillin-1 mutant mouse line C1039G and YAC-transgenic mice (frozen embryos) are available by making request to Hal Dietz. (hdietz@jhmi.edu)
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